Drug Information

Drug General Information
Drug ID
D07LHD
Former ID
DNC005862
Drug Name
1-(2-Dimethylamino-ethyl)-1H-indol-4-ol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527668]
Formula
C12H16N2O
Canonical SMILES
CN(C)CCN1C=CC2=C1C=CC=C2O
InChI
1S/C12H16N2O/c1-13(2)8-9-14-7-6-10-11(14)4-3-5-12(10)15/h3-7,15H,8-9H2,1-2H3
InChIKey
PKWAUGJGYFZHOE-UHFFFAOYSA-N
PubChem Compound ID
44404907
Target and Pathway
Target(s) 5-hydroxytryptamine 2C receptor Target Info Inhibitor [527668]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Serotonergic synapse
Inflammatory mediator regulation of TRP channels
PANTHER Pathway 5HT2 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (q) signalling events
WikiPathways Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 527668Bioorg Med Chem Lett. 2005 Oct 15;15(20):4555-9.SAR of psilocybin analogs: discovery of a selective 5-HT 2C agonist.
Ref 527668Bioorg Med Chem Lett. 2005 Oct 15;15(20):4555-9.SAR of psilocybin analogs: discovery of a selective 5-HT 2C agonist.

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