Details of Protein (Pro) | MIAOME

General Information of Protein (ID: PT017)
Protein Name		cagPAI
Unify Protein name		HP0527-like protein
Protein Entry		E2CYQ3
Protein Entry name		E2CYQ3_HELPX
Protein Length		363AA
Gene name		cagPAI

The epigenetic modification information of this protein
Modification Type																				Molecule																				EM Info								Cell/Tissue Type																		Modified sites																						Condition															REF
Histone Dephosphorylation																				H3																				EM Info								AGS cells																		serine 10																						Helicobacter pylori infection															[1]
Histone Dephosphorylation																				H3																				EM Info								MKN45 cells																		serine 10																						Helicobacter pylori infection															[1]
Histone Acetylation																				H3																				EM Info								.																		lysine 23																						.															[2]

The microbes that produce this protein
Microbiota Name: Helicobacter pylori
Detailed Information		MIC Info click to show the detail information of this Microbiota					[1]
Description		Helicobacter pylori, previously known as Campylobacter pylori, is a gram-negative, helically-shaped, microaerophilic bacteria usually found in the stomach. Helicobacter pylori has been associated with the mucosa-associated lymphoid tissue in the stomach, esophagus, colon, rectum, or tissues around the eye.
Microbiota Name: Helicobacter pylori 26695
Detailed Information		MIC Info click to show the detail information of this Microbiota					[1]
Description		Helicobacter pylori, strain 26695, has a circular genome of 1,667,867 base pairs and 1,590 predictedcoding sequences. Sequence analysis indicates that H. pylori has well-developed systems for motility, forscavenging iron, and for DNA restriction and modification.

References
1	Helicobacter pylori-induced histone modification, associated gene expression in gastric epithelial cells, and its implication in pathogenesis PLoS One. 2010 Apr 1;5(4):e9875. doi: 10.1371/journal.pone.0009875.
2	Bacterial remodelling of the host epigenome: functional role and evolution of effectors methylating host histones Cell Microbiol. 2015 Aug;17(8):1098-107. doi: 10.1111/cmi.12463.

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