Details of Protein (Pro) | MIAOME

General Information of Protein (ID: PT012)
Protein Name		LegAS4
Unify Protein name		Eukaryotic huntingtin interacting protein B
Protein Entry		Q5ZUS4
Protein Entry name		Q5ZUS4_LEGPH
Protein Length		545AA
Gene name		legAS4
Gene Location		57035707

The epigenetic modification information of this protein
Modification Type																				Molecule																				EM Info								Cell/Tissue Type																		Modified sites																						Condition															REF
Histone Trimethylation																				H3																				EM Info								.																		lysine 14																						.															[1]
Histone Methylation																				H3																				EM Info								293T cells																		lysine 4																						.															[2], [3]

The microbes that produce this protein
Microbiota Name: Legionella pneumophila
Detailed Information		MIC Info click to show the detail information of this Microbiota					[3]
Description		Legionella pneumophila is a thin, aerobic, pleomorphic, flagellated, non-spore-forming, gram-negative bacteria of the genus Legionella.
Microbiota Name: Legionella strain philadelphia-1
Detailed Information		MIC Info click to show the detail information of this Microbiota					[2], [3]
Description		Legionella pneumophila is a thin, aerobic, pleomorphic, flagellated, non-spore-forming, gram-negative bacteria of the genus Legionella.
Microbiota Name: Legionella strain Philadelphia
Detailed Information		MIC Info click to show the detail information of this Microbiota					[1]
Description		Legionella pneumophila is a thin, aerobic, pleomorphic, flagellated, non-spore-forming, gram-negative bacteria of the genus Legionella.

References
1	Bacterial Factors Targeting the Nucleus: The Growing Family of Nucleomodulins Toxins (Basel). 2020 Mar 31;12(4):220. doi: 10.3390/toxins12040220.
2	Bacterial remodelling of the host epigenome: functional role and evolution of effectors methylating host histones Cell Microbiol. 2015 Aug;17(8):1098-107. doi: 10.1111/cmi.12463.
3	SET-domain bacterial effectors target heterochromatin protein 1 to activate host rDNA transcription EMBO Rep. 2013 Aug;14(8):733-40. doi: 10.1038/embor.2013.86. Epub 2013 Jun 25.

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