Details of Microbe Species (MIC)

General Information of MIC (ID: MC0998)
  MIC Name
Propionibacterium acidipropionici ATCC 4965
  Lineage Kingdom: Bacteria
Phylum: Actinobacteria
Class: Actinomycetia
Order: Actinomycetales
Family: Propionibacteriaceae
Genus: Propionibacterium
  Oxygen Sensitivity
Facultative anaerobe
  Microbial Metabolism
Saccharolytic; Fermentative
  Gram
Positive
  No. of Coding Genes
2261
  No. of Non-Coding Genes
52
  No. of Small Non-Coding Genes
52
  No. of Gene Transcripts
2313
  Description
Propionibacteria is a gram-positive, anaerobic, rod-shaped genus of bacteria named for their unique metabolism: They are able to synthesize propionic acid by using unusual transcarboxylase enzymes. Its members are primarily facultative parasites and commensals of humans and other animals, living in and around the sweat glands, sebaceous glands, and other areas of the skin.
  External Links
Genome Assembly ID ASM73046v1

Full List of Metabolite(s) Produced by This MIC
     Molecule Type: Fatty acids
           Metabolite Name: Propionate Click to Show/Hide
              Detailed Infomation Meta Info click to show the detail information of this Metabolite
              Metabolic Classification Microbial producted compound [end-products]
Modification Type Molecule EM Info Cell/Tissue Type Modified sites Condition REF
Histone Propionylation H3 EM Info Primary myocytes lysine 23 Health [1], [2]
Histone Propionylation H3K23 EM Info C2C12 cells Myod . [1], [2]


References
1 Propionate hampers differentiation and modifies histone propionylation and acetylation in skeletal muscle cells. Mech Ageing Dev. 2021 Jun;196:111495. doi: 10.1016/j.mad.2021.111495. Epub 2021 Apr 28.
2 Batch fermentation model of propionic acid production by Propionibacterium acidipropionici in different carbon sources Appl Biochem Biotechnol. 2008 Dec;151(2-3):333-41. doi: 10.1007/s12010-008-8196-1. Epub 2008 Apr 2.

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