| General Information of MIC (ID: MC0992) |
| MIC Name |
Ruminococcus gnavus
|
| Lineage |
Kingdom: Bacteria
Phylum: Firmicutes
Class: Clostridia
Order: Eubacteriales
Family: Lachnospiraceae
Genus: Mediterraneibacter
|
| Oxygen Sensitivity |
Obligate anaerobe
|
| Microbial Metabolism |
Saccharolytic; Fermentative
|
| Gram |
Positive
|
| Host Relationship |
Commensal
|
| Genome Size (bp) |
3501911
|
| Description |
Ruminococcus gnavus is an anaerobic gram-negative coccus that can be found in the gastrointestinal tracts of animals and humans. There are only few cases of human infections involving R. gnavus described in the literature. We report a case of septic arthritis caused by R. gnavus in an immunocompromised patient.
|
| External Links |
Taxonomy ID |
33038
|
| GutMDisorder ID |
gm0592
|
| Genome Assembly ID |
ASM16947v1
|
| GOLD Database ID |
Go0005275
|
| GIMICA ID |
MIC01137
|
| Full List of Metabolite(s) Produced by This MIC |
| Molecule Type: Fatty acids |
|---|
| Metabolite Name: Propionate |
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|
| Detailed Infomation |
Meta Info
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|
Metabolic Classification |
Microbial producted compound [end-products] |
| Modification Type |
Molecule |
EM Info |
Cell/Tissue Type |
Modified sites |
Condition |
REF |
| Histone Propionylation |
H3 |
EM Info
|
Primary myocytes |
lysine 23 |
Health |
[1], [2] |
| Histone Propionylation |
H3K23 |
EM Info
|
C2C12 cells |
Myod |
. |
[1], [2] |
| References |
| 1 |
Propionate hampers differentiation and modifies histone propionylation and acetylation in skeletal muscle cells. Mech Ageing Dev. 2021 Jun;196:111495. doi: 10.1016/j.mad.2021.111495. Epub 2021 Apr 28.
|
| 2 |
Gut microbial beta-glucuronidase and glycerol/diol dehydratase activity contribute to dietary heterocyclic amine biotransformation BMC Microbiol. 2019 May 16;19(1):99. doi: 10.1186/s12866-019-1483-x.
|
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