Details of Microbe Species (MIC)

General Information of MIC (ID: MC0991)
  MIC Name
Klebsiella pneumoniae
  Synonym
Bacillus pneumoniae
  Lineage Kingdom: Bacteria
Phylum: Proteobacteria
Class: Gammaproteobacteria
Order: Enterobacterales
Family: Enterobacteriaceae
Genus: Klebsiella
  Oxygen Sensitivity
Facultative anaerobe
  Microbial Metabolism
Fermentative; Respiratory
  Gram
Negative
  Host Relationship
Opportunistic pathogen
  Genome Size (bp)
5682322
  No. of Coding Genes
5514
  No. of Non-Coding Genes
201
  No. of Small Non-Coding Genes
201
  No. of Gene Transcripts
5730
  No. of Pseudogenes 15
  No. of Base Pairs
5781501
  Description
Klebsiella pneumoniae is a facultative anaerobic, gram-negative, non-motile, encapsulated, lactose-fermenting, rod-shaped bacteria. In the clinical setting, it is the most significant member of the genus Klebsiella of the Enterobacteriaceae. Although found in the normal flora of the mouth, skin and intestines, it can cause destructive changes to human and animal lungs if aspirated, specifically to the alveoli resulting in bloody, brownish or yellow colored jelly like sputum.
  External Links Taxonomy ID 573
GutMDisorder ID gm0380
Genome Assembly ID ASM36438v3
GOLD Database ID Go0005342
GIMICA ID MIC01405

Full List of Metabolite(s) Produced by This MIC
     Molecule Type: Fatty acids
           Metabolite Name: Propionate Click to Show/Hide
              Detailed Infomation Meta Info click to show the detail information of this Metabolite
              Metabolic Classification Microbial producted compound [end-products]
Modification Type Molecule EM Info Cell/Tissue Type Modified sites Condition REF
Histone Propionylation H3 EM Info Primary myocytes lysine 23 Health [1], [2]
Histone Propionylation H3K23 EM Info C2C12 cells Myod . [1], [2]


References
1 Propionate hampers differentiation and modifies histone propionylation and acetylation in skeletal muscle cells. Mech Ageing Dev. 2021 Jun;196:111495. doi: 10.1016/j.mad.2021.111495. Epub 2021 Apr 28.
2 Gut microbial beta-glucuronidase and glycerol/diol dehydratase activity contribute to dietary heterocyclic amine biotransformation BMC Microbiol. 2019 May 16;19(1):99. doi: 10.1186/s12866-019-1483-x.

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