General Information of MIC (ID: MC0674)
  MIC Name
Weissella paramesenteroides ATCC 33313
  Lineage Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Lactobacillales
Family: Leuconostocaceae
Genus: Weissella
  Oxygen Sensitivity
Facultative anaerobe
  Microbial Metabolism
Saccharolytic; Respiratory or Fermentative
  Gram
Positive
  Host Relationship
Commensal
  Genome Size (bp)
1962173
  No. of Coding Genes
1952
  No. of Non-Coding Genes
68
  No. of Small Non-Coding Genes
68
  No. of Gene Transcripts
2020
  Description
Weissella paramesenteroides ATCC 33313 is a gram-positive and facultative anaerobic strain from the genus of Weissella.
  External Links Taxonomy ID 585506
Genome Assembly ID ASM16057v1
GOLD Database ID Go0003391

Full List of Metabolite(s) Produced by This MIC
     Molecule Type: Fatty acids
           Metabolite Name: Acetate Click to Show/Hide
              Detailed Infomation Meta Info click to show the detail information of this Metabolite
              Metabolic Classification Microbial producted compound [end-products]
Modification Type Molecule EM Info Cell/Tissue Type Modified sites Condition REF
Histone Acetylation H3K27 EM Info HepG2 cells ACACA promoter Hypoxia [1], [2]
Histone Acetylation H3K27 EM Info HepG2 cells FASN promoter Hypoxia [1], [2]
Histone Acetylation H3K27 EM Info HepG2 cells LDHA promoter Hypoxia [1], [2]
Histone Acetylation H3K27 EM Info HepG2 cells VEGF promoter Hypoxia [1], [2]
Histone Acetylation H3K56 EM Info HepG2 cells ACACA promoter Hypoxia [1], [2]
Histone Acetylation H3K56 EM Info HepG2 cells FASN promoter Hypoxia [1], [2]
Histone Acetylation H3K56 EM Info HepG2 cells LDHA promoter Hypoxia [1], [2]
Histone Acetylation H3K56 EM Info HepG2 cells VEGF promoter Hypoxia [1], [2]
Histone Acetylation H3K9 EM Info HepG2 cells ACACA promoter Hypoxia [1], [2]
Histone Acetylation H3K9 EM Info HepG2 cells FASN promoter Hypoxia [1], [2]
Histone Acetylation H3K9 EM Info HepG2 cells LDHA promoter Hypoxia [1], [2]
Histone Acetylation H3K9 EM Info HepG2 cells VEGF promoter Hypoxia [1], [2]
Histone Deacetylation HDAC9 EM Info Eosinophil cell . Asthma [3], [2]


References
1 Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia. Nat Commun. 2016 Jun 30;7:11960. doi: 10.1038/ncomms11960.
2 The Virtual Metabolic Human database: integrating human and gut microbiome metabolism with nutrition and disease. Nucleic Acids Res. 2019 Jan 8;47(D1):D614-D624. doi: 10.1093/nar/gky992.
3 Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites. Nat Commun. 2015 Jun 23;6:7320. doi: 10.1038/ncomms8320.

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