General Information of MIC (ID: MC0375)
  MIC Name
Enterococcus dispar ATCC 51266
  Synonym
Enterococcus dispar CCUG 33309, Enterococcus dispar CIP 103646, Enterococcus dispar EnGen0385, Enterococcus dispar LMG 13521, Enterococcus dispar NBRC 100678, Enterococcus dispar NCIMB 13000
  Lineage Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Lactobacillales
Family: Enterococcaceae
Genus: Enterococcus
  Oxygen Sensitivity
Facultative anaerobe
  Microbial Metabolism
Saccharolytic; Fermentative
  Gram
Positive
  Host Relationship
Commensal
  Genome Size (bp)
2812918
  No. of Coding Genes
2636
  No. of Non-Coding Genes
80
  No. of Small Non-Coding Genes
80
  No. of Gene Transcripts
2716
  Description
Enterococcus dispar ATCC 51266 is a strain of facultative anaerobic, gram-positive, saccharolytic bacteria.
  External Links Taxonomy ID 1139219
Genome Assembly ID Ente_disp_ATCC51266_V1
GOLD Database ID Go0020514

Full List of Metabolite(s) Produced by This MIC
     Molecule Type: Fatty acids
           Metabolite Name: Acetate Click to Show/Hide
              Detailed Infomation Meta Info click to show the detail information of this Metabolite
              Metabolic Classification Microbial producted compound [end-products]
Modification Type Molecule EM Info Cell/Tissue Type Modified sites Condition REF
Histone Acetylation H3K27 EM Info HepG2 cells ACACA promoter Hypoxia [1], [2]
Histone Acetylation H3K27 EM Info HepG2 cells FASN promoter Hypoxia [1], [2]
Histone Acetylation H3K27 EM Info HepG2 cells LDHA promoter Hypoxia [1], [2]
Histone Acetylation H3K27 EM Info HepG2 cells VEGF promoter Hypoxia [1], [2]
Histone Acetylation H3K56 EM Info HepG2 cells ACACA promoter Hypoxia [1], [2]
Histone Acetylation H3K56 EM Info HepG2 cells FASN promoter Hypoxia [1], [2]
Histone Acetylation H3K56 EM Info HepG2 cells LDHA promoter Hypoxia [1], [2]
Histone Acetylation H3K56 EM Info HepG2 cells VEGF promoter Hypoxia [1], [2]
Histone Acetylation H3K9 EM Info HepG2 cells ACACA promoter Hypoxia [1], [2]
Histone Acetylation H3K9 EM Info HepG2 cells FASN promoter Hypoxia [1], [2]
Histone Acetylation H3K9 EM Info HepG2 cells LDHA promoter Hypoxia [1], [2]
Histone Acetylation H3K9 EM Info HepG2 cells VEGF promoter Hypoxia [1], [2]
Histone Deacetylation HDAC9 EM Info Eosinophil cell . Asthma [3], [2]
           Metabolite Name: Lactate Click to Show/Hide
              Detailed Infomation Meta Info click to show the detail information of this Metabolite
              Metabolic Classification Microbial producted compound [end-products]
Modification Type Molecule EM Info Cell/Tissue Type Modified sites Condition REF
miRNA miR-141-3P EM Info Oral epithelial cells . Autistic spectrum disorder [4], [2]


References
1 Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia. Nat Commun. 2016 Jun 30;7:11960. doi: 10.1038/ncomms11960.
2 The Virtual Metabolic Human database: integrating human and gut microbiome metabolism with nutrition and disease. Nucleic Acids Res. 2019 Jan 8;47(D1):D614-D624. doi: 10.1093/nar/gky992.
3 Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites. Nat Commun. 2015 Jun 23;6:7320. doi: 10.1038/ncomms8320.
4 Potential Associations Among Alteration of Salivary miRNAs, Saliva Microbiome Structure, and Cognitive Impairments in Autistic Children. Int J Mol Sci. 2020 Aug 27;21(17):6203. doi: 10.3390/ijms21176203.

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