| General Information of MIC (ID: MC0105) |
| MIC Name |
Lactobacillus brevis
|
| Synonym |
Betabacterium breve
|
| Lineage |
Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Lactobacillales
Family: Lactobacillaceae
Genus: Levilactobacillus
|
| Oxygen Sensitivity |
Aaerobe
|
| Microbial Metabolism |
Saccharolytic; Fermentative
|
| Gram |
Positive
|
| Genome Size (bp) |
2340228
|
| No. of Coding Genes |
2788
|
| No. of Non-Coding Genes |
66
|
| No. of Small Non-Coding Genes |
66
|
| No. of Gene Transcripts |
2854
|
| No. of Base Pairs |
2864217
|
| Description |
Lactobacillus brevis is a gram-positive, rod shaped species of lactic acid bacteria, there are approximately 16 different strains.
|
| External Links |
Taxonomy ID |
1580
|
| GutMDisorder ID |
gm0393
|
| Genome Assembly ID |
ASM81472v1
|
| GOLD Database ID |
Go0000287
|
| GIMICA ID |
MIC00705
|
| Full List of Metabolite(s) Produced by This MIC |
| Molecule Type: Fatty acids |
|---|
| Metabolite Name: Acetate |
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|
| Detailed Infomation |
Meta Info
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|
Metabolic Classification |
Microbial producted compound [end-products] |
| Modification Type |
Molecule |
EM Info |
Cell/Tissue Type |
Modified sites |
Condition |
REF |
| Histone Acetylation |
H4 |
EM Info
|
Eosinophil cell |
Foxo3A promoter |
Asthma |
[1], [2] |
| Histone Acetylation |
H3K27 |
EM Info
|
HepG2 cells |
FASN promoter |
Hypoxia |
[3], [2] |
| Histone Acetylation |
H3K27 |
EM Info
|
HepG2 cells |
LDHA promoter |
Hypoxia |
[3], [2] |
| Histone Acetylation |
H3K56 |
EM Info
|
HepG2 cells |
FASN promoter |
Hypoxia |
[3], [2] |
| Histone Acetylation |
H3K9 |
EM Info
|
HepG2 cells |
ACACA promoter |
Hypoxia |
[3], [2] |
| Histone Acetylation |
H3K9 |
EM Info
|
HepG2 cells |
LDHA promoter |
Hypoxia |
[3], [2] |
| Histone Deacetylation |
HDAC9 |
EM Info
|
Eosinophil cell |
. |
Asthma |
[1], [2] |
| References |
| 1 |
Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites. Nat Commun. 2015 Jun 23;6:7320. doi: 10.1038/ncomms8320.
|
| 2 |
Screening of surface properties and antagonistic substances production by lactic acid bacteria isolated from the mammary gland of healthy and mastitic cows Vet Microbiol. 2009 Mar 30;135(3-4):346-57. doi: 10.1016/j.vetmic.2008.09.078. Epub 2008 Oct 8.
|
| 3 |
Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia. Nat Commun. 2016 Jun 30;7:11960. doi: 10.1038/ncomms11960.
|
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