Details of Microbe Species (MIC)

General Information of MIC (ID: MC0084)
  MIC Name
Staphylococcus aureus
  Synonym
Staphylococcus pyogenes aureus
  Lineage Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Bacillales
Family: Staphylococcaceae
Genus: Staphylococcus
  Oxygen Sensitivity
Facultative anaerobe
  Microbial Metabolism
Saccharolytic; Respiratory or Fermentative
  Gram
Positive
  Host Relationship
Opportunistic pathogen
  Genome Size (bp)
2787689
  No. of Coding Genes
2500
  No. of Non-Coding Genes
78
  No. of Small Non-Coding Genes
78
  No. of Gene Transcripts
2578
  No. of Base Pairs
2787689
  Description
Staphylococcus aureus is a gram-positive, round-shaped bacteria that is a member of the Firmicutes, and it is a usual member of the microbiota of the body, frequently found in the upper respiratory tract and on the skin.
  External Links Taxonomy ID 1280
GutMDisorder ID gm0621
Genome Assembly ID ASM59796v1
GOLD Database ID Go0037024
GIMICA ID MIC01208

Full List of Metabolite(s) Produced by This MIC
     Molecule Type: Fatty acids
           Metabolite Name: Acetate Click to Show/Hide
              Detailed Infomation Meta Info click to show the detail information of this Metabolite
              Metabolic Classification Microbial producted compound [end-products]
Modification Type Molecule EM Info Cell/Tissue Type Modified sites Condition REF
Histone Acetylation H4 EM Info Eosinophil cell Foxo3A promoter Asthma [1], [2]
Histone Acetylation H3K27 EM Info HepG2 cells FASN promoter Hypoxia [3], [2]
Histone Acetylation H3K27 EM Info HepG2 cells LDHA promoter Hypoxia [3], [2]
Histone Acetylation H3K56 EM Info HepG2 cells FASN promoter Hypoxia [3], [2]
Histone Acetylation H3K9 EM Info HepG2 cells ACACA promoter Hypoxia [3], [2]
Histone Acetylation H3K9 EM Info HepG2 cells LDHA promoter Hypoxia [3], [2]
Histone Deacetylation HDAC9 EM Info Eosinophil cell . Asthma [1], [2]


References
1 Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites. Nat Commun. 2015 Jun 23;6:7320. doi: 10.1038/ncomms8320.
2 Comparison of Stir Bar Sorptive Extraction and Solid Phase Microextraction of Volatile and Semi-Volatile Metabolite Profile of Staphylococcus Aureus Molecules. 2019 Dec 23;25(1):55. doi: 10.3390/molecules25010055.
3 Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia. Nat Commun. 2016 Jun 30;7:11960. doi: 10.1038/ncomms11960.

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