| General Information of MIC (ID: MC0082) |
| MIC Name |
Lactococcus sp.
|
| Lineage |
Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Lactobacillales
Family: Streptococcaceae
Genus: Lactococcus
|
| Oxygen Sensitivity |
Facultative anaerobe
|
| Microbial Metabolism |
Saccharolytic; Respiratory or Fermentative
|
| Gram |
Positive
|
| No. of Coding Genes |
1692
|
| No. of Non-Coding Genes |
35
|
| No. of Small Non-Coding Genes |
35
|
| No. of Gene Transcripts |
1757
|
| No. of Pseudogenes |
30
|
| Description |
Lactococcus sp. is a species of gram-positive, facultative anaerobic bacteria from the genus Lactococcus.
|
| External Links |
Taxonomy ID |
44273
|
| Genome Assembly ID |
ASM353567v1
|
| Full List of Metabolite(s) Produced by This MIC |
| Molecule Type: Fatty acids |
|---|
| Metabolite Name: Acetate |
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|
| Detailed Infomation |
Meta Info
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|
Metabolic Classification |
Microbial producted compound [end-products] |
| Modification Type |
Molecule |
EM Info |
Cell/Tissue Type |
Modified sites |
Condition |
REF |
| Histone Acetylation |
H4 |
EM Info
|
Eosinophil cell |
Foxo3A promoter |
Asthma |
[1], [2] |
| Histone Acetylation |
H3K27 |
EM Info
|
HepG2 cells |
FASN promoter |
Hypoxia |
[3], [2] |
| Histone Acetylation |
H3K27 |
EM Info
|
HepG2 cells |
LDHA promoter |
Hypoxia |
[3], [2] |
| Histone Acetylation |
H3K56 |
EM Info
|
HepG2 cells |
FASN promoter |
Hypoxia |
[3], [2] |
| Histone Acetylation |
H3K9 |
EM Info
|
HepG2 cells |
ACACA promoter |
Hypoxia |
[3], [2] |
| Histone Acetylation |
H3K9 |
EM Info
|
HepG2 cells |
LDHA promoter |
Hypoxia |
[3], [2] |
| Histone Deacetylation |
HDAC9 |
EM Info
|
Eosinophil cell |
. |
Asthma |
[1], [2] |
| References |
| 1 |
Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites. Nat Commun. 2015 Jun 23;6:7320. doi: 10.1038/ncomms8320.
|
| 2 |
Less biomass and intracellular glutamate in anodic biofilms lead to efficient electricity generation by microbial fuel cells Biotechnol Biofuels. 2019 Apr 1;12:72. doi: 10.1186/s13068-019-1414-y. eCollection 2019.
|
| 3 |
Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia. Nat Commun. 2016 Jun 30;7:11960. doi: 10.1038/ncomms11960.
|
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