General Information of MIC (ID: MC0081)
  MIC Name
Thermoanaerobacter finnii
  Synonym
Thermoanaerobacter finnii
  Lineage Kingdom: Bacteria
Phylum: Firmicutes
Class: Clostridia
Order: Thermoanaerobacterales
Family: Thermoanaerobacteraceae
Genus: Thermoanaerobacter
  Oxygen Sensitivity
Anaerobe
  Microbial Metabolism
Saccharolytic; Fermentative
  Gram
Positive
  Description
Thermoanaerobacter brockii subsp. finnii is a subspecies of gram-positive, anaerobic bacteria from the species Thermoanaerobacter brockii.
  External Links Taxonomy ID 29325

Full List of Metabolite(s) Produced by This MIC
     Molecule Type: Fatty acids
           Metabolite Name: Acetate Click to Show/Hide
              Detailed Infomation Meta Info click to show the detail information of this Metabolite
              Metabolic Classification Microbial producted compound [end-products]
Modification Type Molecule EM Info Cell/Tissue Type Modified sites Condition REF
Histone Acetylation H4 EM Info Eosinophil cell Foxo3A promoter Asthma [1], [2]
Histone Acetylation H3K27 EM Info HepG2 cells FASN promoter Hypoxia [3], [2]
Histone Acetylation H3K27 EM Info HepG2 cells LDHA promoter Hypoxia [3], [2]
Histone Acetylation H3K56 EM Info HepG2 cells FASN promoter Hypoxia [3], [2]
Histone Acetylation H3K9 EM Info HepG2 cells ACACA promoter Hypoxia [3], [2]
Histone Acetylation H3K9 EM Info HepG2 cells LDHA promoter Hypoxia [3], [2]
Histone Deacetylation HDAC9 EM Info Eosinophil cell . Asthma [1], [2]


References
1 Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites. Nat Commun. 2015 Jun 23;6:7320. doi: 10.1038/ncomms8320.
2 Effect of thiosulphate as electron acceptor on glucose and xylose oxidation by Thermoanaerobacter finnii and a Thermoanaerobacter sp. isolated from oil field water Res Microbiol. 1996 Mar-Apr;147(3):159-65. doi: 10.1016/0923-2508(96)80215-4.
3 Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia. Nat Commun. 2016 Jun 30;7:11960. doi: 10.1038/ncomms11960.

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