| General Information of MIC (ID: MC0065) |
| MIC Name |
Bifidobacterium longum subsp. Infantis
|
| Lineage |
Kingdom: Bacteria
Phylum: Actinobacteria
Class: Actinomycetia
Order: Bifidobacteriales
Family: Bifidobacteriaceae
Genus: Bifidobacterium
|
| Oxygen Sensitivity |
Obligate anaerobe
|
| Microbial Metabolism |
Saccharolytic; Fermentative
|
| Gram |
Positive
|
| Host Relationship |
Probiotic
|
| Genome Size (bp) |
2821883
|
| No. of Coding Genes |
2556
|
| No. of Non-Coding Genes |
84
|
| No. of Small Non-Coding Genes |
84
|
| No. of Gene Transcripts |
2640
|
| No. of Base Pairs |
2821883
|
| Description |
Bifidobacteria longum infantis is a bifidobacteria that is found in the digestive tract of human infants. It is more accurately called Bifidobacteria longum subsp. infantis.
|
| External Links |
Taxonomy ID |
1682
|
| GutMDisorder ID |
gm0112
|
| Genome Assembly ID |
BIC1401212621b.V1
|
| GOLD Database ID |
Go0506786
|
| GIMICA ID |
MIC00215
|
| Full List of Metabolite(s) Produced by This MIC |
| Molecule Type: Fatty acids |
|---|
| Metabolite Name: Acetate |
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|
| Detailed Infomation |
Meta Info
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|
Metabolic Classification |
Microbial producted compound [end-products] |
| Modification Type |
Molecule |
EM Info |
Cell/Tissue Type |
Modified sites |
Condition |
REF |
| Histone Acetylation |
H4 |
EM Info
|
Eosinophil cell |
Foxo3A promoter |
Asthma |
[1], [2] |
| Histone Acetylation |
H3K27 |
EM Info
|
HepG2 cells |
FASN promoter |
Hypoxia |
[3], [2] |
| Histone Acetylation |
H3K27 |
EM Info
|
HepG2 cells |
LDHA promoter |
Hypoxia |
[3], [2] |
| Histone Acetylation |
H3K56 |
EM Info
|
HepG2 cells |
FASN promoter |
Hypoxia |
[3], [2] |
| Histone Acetylation |
H3K9 |
EM Info
|
HepG2 cells |
ACACA promoter |
Hypoxia |
[3], [2] |
| Histone Acetylation |
H3K9 |
EM Info
|
HepG2 cells |
LDHA promoter |
Hypoxia |
[3], [2] |
| Histone Deacetylation |
HDAC9 |
EM Info
|
Eosinophil cell |
. |
Asthma |
[1], [2] |
| References |
| 1 |
Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites. Nat Commun. 2015 Jun 23;6:7320. doi: 10.1038/ncomms8320.
|
| 2 |
Growth and final product formation by Bifidobacterium infantis in aerated fermentations Appl Microbiol Biotechnol. 2004 Oct;65(5):606-10. doi: 10.1007/s00253-004-1603-9. Epub 2004 Apr 14.
|
| 3 |
Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia. Nat Commun. 2016 Jun 30;7:11960. doi: 10.1038/ncomms11960.
|
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