| General Information of MIC (ID: MC0057) |
| MIC Name |
Bacillus siamensis
|
| Synonym |
Bacillus vanillea
|
| Lineage |
Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Bacillales
Family: Bacillaceae
Genus: Bacillus
|
| Oxygen Sensitivity |
Anaerobe
|
| Microbial Metabolism |
Saccharolytic; Fermentative
|
| Gram |
Positive
|
| No. of Coding Genes |
3668
|
| No. of Non-Coding Genes |
58
|
| No. of Small Non-Coding Genes |
58
|
| No. of Gene Transcripts |
3805
|
| No. of Pseudogenes |
79
|
| Description |
Bacillus siamensis is a facultative anaerobic, spore-forming, mesophilic bacteria from the genus Bacillus.
|
| External Links |
Taxonomy ID |
659243
|
| Genome Assembly ID |
assembly-7551_v1
|
| Full List of Metabolite(s) Produced by This MIC |
| Molecule Type: Fatty acids |
|---|
| Metabolite Name: Acetate |
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|
| Detailed Infomation |
Meta Info
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|
Metabolic Classification |
Microbial producted compound [end-products] |
| Modification Type |
Molecule |
EM Info |
Cell/Tissue Type |
Modified sites |
Condition |
REF |
| Histone Acetylation |
H4 |
EM Info
|
Eosinophil cell |
Foxo3A promoter |
Asthma |
[1], [2] |
| Histone Acetylation |
H3K27 |
EM Info
|
HepG2 cells |
FASN promoter |
Hypoxia |
[3], [2] |
| Histone Acetylation |
H3K27 |
EM Info
|
HepG2 cells |
LDHA promoter |
Hypoxia |
[3], [2] |
| Histone Acetylation |
H3K56 |
EM Info
|
HepG2 cells |
FASN promoter |
Hypoxia |
[3], [2] |
| Histone Acetylation |
H3K9 |
EM Info
|
HepG2 cells |
ACACA promoter |
Hypoxia |
[3], [2] |
| Histone Acetylation |
H3K9 |
EM Info
|
HepG2 cells |
LDHA promoter |
Hypoxia |
[3], [2] |
| Histone Deacetylation |
HDAC9 |
EM Info
|
Eosinophil cell |
. |
Asthma |
[1], [2] |
| References |
| 1 |
Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites. Nat Commun. 2015 Jun 23;6:7320. doi: 10.1038/ncomms8320.
|
| 2 |
Genomic and metabolic features of the Bacillus amyloliquefaciens group- B. amyloliquefaciens, B. velezensis, and B. siamensis- revealed by pan-genome analysis Food Microbiol. 2019 Feb;77:146-157. doi: 10.1016/j.fm.2018.09.001. Epub 2018 Sep 5.
|
| 3 |
Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia. Nat Commun. 2016 Jun 30;7:11960. doi: 10.1038/ncomms11960.
|
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