Details of Microbe Species (MIC)

General Information of MIC (ID: MC0041)
  MIC Name
Haemophilus influenzae
  Synonym
Bacterium influenzae, Coccobacillus pfeifferi, Haemophilus meningitidis, Influenza-bacillus, Mycobacterium influenzae
  Lineage Kingdom: Bacteria
Phylum: Proteobacteria
Class: Gammaproteobacteria
Order: Pasteurellales
Family: Pasteurellaceae
Genus: Haemophilus
  Oxygen Sensitivity
Facultative anaerobe
  Microbial Metabolism
Saccharolytic; Fermentative
  Gram
Negative
  Host Relationship
Pathogen; Commensal
  No. of Coding Genes
1668
  No. of Non-Coding Genes
51
  No. of Small Non-Coding Genes
51
  No. of Gene Transcripts
1719
  No. of Base Pairs
1787944
  Description
Haemophilus influenzae is a gram-negative, coccobacillary, facultatively anaerobic capnophilic pathogenic bacteria of the family Pasteurellaceae.
  External Links Taxonomy ID 727
GutMDisorder ID gm0357
Genome Assembly ID ASM298534v1
GOLD Database ID Go0005539
GIMICA ID MIC00652

Full List of Metabolite(s) Produced by This MIC
     Molecule Type: Fatty acids
           Metabolite Name: Acetate Click to Show/Hide
              Detailed Infomation Meta Info click to show the detail information of this Metabolite
              Metabolic Classification Microbial producted compound [end-products]
Modification Type Molecule EM Info Cell/Tissue Type Modified sites Condition REF
Histone Acetylation H4 EM Info Eosinophil cell Foxo3A promoter Asthma [1], [2]
Histone Acetylation H3K27 EM Info HepG2 cells FASN promoter Hypoxia [3], [2]
Histone Acetylation H3K27 EM Info HepG2 cells LDHA promoter Hypoxia [3], [2]
Histone Acetylation H3K56 EM Info HepG2 cells FASN promoter Hypoxia [3], [2]
Histone Acetylation H3K9 EM Info HepG2 cells ACACA promoter Hypoxia [3], [2]
Histone Acetylation H3K9 EM Info HepG2 cells LDHA promoter Hypoxia [3], [2]
Histone Deacetylation HDAC9 EM Info Eosinophil cell . Asthma [1], [2]


References
1 Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites. Nat Commun. 2015 Jun 23;6:7320. doi: 10.1038/ncomms8320.
2 Metabolic versatility in Haemophilus influenzae: a metabolomic and genomic analysis Front Microbiol. 2014 Mar 4;5:69. doi: 10.3389/fmicb.2014.00069. eCollection 2014.
3 Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia. Nat Commun. 2016 Jun 30;7:11960. doi: 10.1038/ncomms11960.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.