| General Information of MIC (ID: MC0040) |
| MIC Name |
Vibrio cholerae
|
| Lineage |
Kingdom: Bacteria
Phylum: Proteobacteria
Class: Gammaproteobacteria
Order: Vibrionales
Family: Vibrionaceae
Genus: Vibrio
|
| Oxygen Sensitivity |
Facultative anaerobe
|
| Microbial Metabolism |
Fermentative; Respiratory
|
| Gram |
Negative
|
| Host Relationship |
Pathogen
|
| No. of Coding Genes |
3774
|
| No. of Gene Transcripts |
3774
|
| No. of Base Pairs |
4012216
|
| Description |
Vibrio cholerae is a species of gram-negative, facultative anaerobic and comma-shaped bacteria from the genus Vibrio.
|
| External Links |
Taxonomy ID |
666
|
| GutMDisorder ID |
gm0685
|
| Genome Assembly ID |
V.cholerae116-17a
|
| GOLD Database ID |
Go0526281
|
| GIMICA ID |
MIC01369
|
| Full List of Metabolite(s) Produced by This MIC |
| Molecule Type: Fatty acids |
|---|
| Metabolite Name: Acetate |
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|
| Detailed Infomation |
Meta Info
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|
Metabolic Classification |
Microbial producted compound [end-products] |
| Modification Type |
Molecule |
EM Info |
Cell/Tissue Type |
Modified sites |
Condition |
REF |
| Histone Acetylation |
H4 |
EM Info
|
Eosinophil cell |
Foxo3A promoter |
Asthma |
[1], [2] |
| Histone Acetylation |
H3K27 |
EM Info
|
HepG2 cells |
FASN promoter |
Hypoxia |
[3], [2] |
| Histone Acetylation |
H3K27 |
EM Info
|
HepG2 cells |
LDHA promoter |
Hypoxia |
[3], [2] |
| Histone Acetylation |
H3K56 |
EM Info
|
HepG2 cells |
FASN promoter |
Hypoxia |
[3], [2] |
| Histone Acetylation |
H3K9 |
EM Info
|
HepG2 cells |
ACACA promoter |
Hypoxia |
[3], [2] |
| Histone Acetylation |
H3K9 |
EM Info
|
HepG2 cells |
LDHA promoter |
Hypoxia |
[3], [2] |
| Histone Deacetylation |
HDAC9 |
EM Info
|
Eosinophil cell |
. |
Asthma |
[1], [2] |
| References |
| 1 |
Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites. Nat Commun. 2015 Jun 23;6:7320. doi: 10.1038/ncomms8320.
|
| 2 |
A Putative Acetylation System in Vibrio cholerae Modulates Virulence in Arthropod Hosts Appl Environ Microbiol. 2018 Oct 17;84(21):e01113-18. doi: 10.1128/AEM.01113-18. Print 2018 Nov 1.
|
| 3 |
Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia. Nat Commun. 2016 Jun 30;7:11960. doi: 10.1038/ncomms11960.
|
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