General Information of Metabolite (ID: MT046)
  Meta Name
phenylbutyl isothiocyanate
  Unify Name
phenylbutyl isothiocyanate
  Molecule Type
Other metabolites
  Description    Click to Show/Hide the Detailed Description of This Metabolite
Phenylbutyl isothiocyanate is a synthetic phenyl alkyl isothiocyanate that has displayed induction of Phase II detoxifying enzymes. Also inhibits chemically induced carcinogenesis.

The epigenetic modification information of this metabolite
Modification Type Molecule EM Info Cell/Tissue Type Modified sites Condition REF
Histone Deacetylation HDAC EM Info . . . [1], [2]

The microbes that produce this metabolite
      Enterococcus casseliflavus CP1
         Detailed Information MIC Info click to show the detail information of this Microbiota [1], [2]
         Description
Enterococcus casseliflavus CP1 is a strain of facultative anaerobic, gram-positive, saccharolytic bacteria.
      Lactobacillus agilis R16
         Detailed Information MIC Info click to show the detail information of this Microbiota [1], [2]
         Description
Lactobacillus agilis R16 is a strain of gram-positive, aerotolerant anaerobics or microaerophilic, rod-shaped, non-spore-forming bacteria.
      Escherichia coli VL8
         Detailed Information MIC Info click to show the detail information of this Microbiota [1], [2]
         Description
The Escherichia coli VL8 is a strain of gram-negative, anaerobic bacteria from the species Escherichia coli.

References
1 Influence of bacteria on epigenetic gene control. Cell Mol Life Sci. 2014 Mar;71(6):1045-54. doi: 10.1007/s00018-013-1487-x. Epub 2013 Oct 15.
2 Broccoli ingestion increases the glucosinolate hydrolysis activity of microbiota in the mouse gut Int J Food Sci Nutr. 2019 Aug;70(5):585-594. doi: 10.1080/09637486.2018.1554624. Epub 2019 Feb 16.

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