Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM12233)
  Official Symbol
MST1
  Official Full Name
Macrophage Stimulating 1
  Synonym
Macrophage Stimulating 1;D3F15S2;DNF15S2;NF15S2;HGFL;MSP;Macrophage Stimulatory Protein;Hepatocyte Growth Factor-Like;EC 3.4.21;Macrophage Stimulating 1 (Hepatocyte Growth Factor-Like);Macrophage-Stimulating Protein;Hepatocyte Growth Factor-Like Protein
  Molecule Type
Protein coding
  Position On Chromosome
chr3(Start:49683947 - End:49689523)
  Strand
-
  Uniprot Entry
P26927 
  ENSG ID
ENSG00000173531 
    Disease Relevance (Click to Show/Hide)
         2C30: Melanoma of skin Cutaneous Melanoma [Melanoma of skin]
            Detailed Information Disease Link click to show the detail information of this Disease
         8A20: Alzheimer disease Alzheimer's disease [Alzheimer disease]
            Detailed Information Disease Link click to show the detail information of this Disease
         CB03: Idiopathic interstitial pneumonitis Idiopathic pulmonary fibrosis (IPF) [Idiopathic interstitial pneumonitis]
            Detailed Information Disease Link click to show the detail information of this Disease
         SE30: Developmental delay disorder CHARGE and Kabuki syndromes [Developmental delay disorder]
            Detailed Information Disease Link click to show the detail information of this Disease
         XH4XG8: Chronic myeloid leukaemia Chronic Phase-Chronic Myeloid Leukemia [Chronic myeloid leukaemia]
            Detailed Information Disease Link click to show the detail information of this Disease
Metabolite(s) with this epigenetic modification
  Metabolite Name: Resveratrol
     Detailed Information Meta Info click to show the detail information of this Metabolite [1], [2]
     Description
Resveratrol could change tumor suppressor gene MST1 from hypermethylated to hypomethylated status in MDA-MB-231 breast cancer cells treated with resveratrol (100 M) at 48 h.

References
1 Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597.
2 Methylation Landscape of Human Breast Cancer Cells in Response to Dietary Compound Resveratrol. PLoS One. 2016 Jun 29;11(6):e0157866. doi: 10.1371/journal.pone.0157866. eCollection 2016.

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