Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM11970)
  Official Symbol
CCL3
  Official Full Name
C-C Motif Chemokine Ligand 3
  Synonym
C-C Motif Chemokine Ligand 3;MIP-1-Alpha;G0S19-1;LD78ALPHA;SCYA3;Macrophage Inflammatory Protein 1-Alpha;MIP1A;Chemokine (C-C Motif) Ligand 3;Small-Inducible Cytokine A
  Molecule Type
Protein coding
  Position On Chromosome
chr17(Start:36088256 - End:36088256)
  Strand
-
  Uniprot Entry
P10147 
  ENSG ID
ENSG00000277632 
Metabolite(s) with this epigenetic modification
  Metabolite Name: Cobalamin (B12)
     Detailed Information Meta Info click to show the detail information of this Metabolite [1], [2]
     Description
Cobalamin (B12) has been shown to induce hypermethylation of CpGs at the promoter of Ccl3 in the hippocampus during bacterial meningitis.
  Metabolite Name: Folate (B9)
     Detailed Information Meta Info click to show the detail information of this Metabolite [1], [2]
     Description
Folate (B9) could induce hypermethylation of CpGs at the promoter of Ccl3 in the hippocampus during Bacterial meningitis.

References
1 Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597.
2 Arachidonic and oleic acid exert distinct effects on the DNA methylome. Epigenetics. 2016 May 3;11(5):321-34. doi: 10.1080/15592294.2016.1161873. Epub 2016 Apr 18.

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