Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM11952)
  Official Symbol
C9orf163
  Official Full Name
Chromosome 9 Putative Open Reading Frame 163
  Synonym
Chromosome 9 Putative Open Reading Frame 163;Uncharacterized Protein C9orf163;FLJ36779;Chromosome 9 Open Reading Frame 163;Lnc-PMPCA-3
  Molecule Type
Protein coding
  Position On Chromosome
chr9(Start:136483494 - End:136486067)
  Strand
+
  Uniprot Entry
Q8N9P6 
  ENSG ID
ENSG00000196366 
    Disease Relevance (Click to Show/Hide)
         8A20: Alzheimer disease Alzheimer's disease [Alzheimer disease]
            Detailed Information Disease Link click to show the detail information of this Disease
         LD2C: Overgrowth syndromes Sotos syndrome(SS) [Overgrowth syndromes]
            Detailed Information Disease Link click to show the detail information of this Disease
Metabolite(s) with this epigenetic modification
  Metabolite Name: Arachidonic acid
     Detailed Information Meta Info click to show the detail information of this Metabolite [1], [2]
     Description
Arachidonic acid could induce C9orf163 gene hypermethylation in THP-1 cells.

References
1 Histone Methylation Dynamics and Gene Regulation Occur through the Sensing of One-Carbon Metabolism. Cell Metab. 2015 Nov 3;22(5):861-73. doi: 10.1016/j.cmet.2015.08.024. Epub 2015 Sep 24.
2 Synergistic Effect in Core Microbiota Associated with Sulfur Metabolism in Spontaneous Chinese Liquor Fermentation Appl Environ Microbiol. 2017 Dec 1;83(24):e01475-17. doi: 10.1128/AEM.01475-17. Print 2017 Dec 15.

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