Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM11900)
  Official Symbol
BMP3
  Official Full Name
Bone Morphogenetic Protein 3
  Synonym
Bone Morphogenetic Protein 3;Osteogenin;Bone Morphogenetic Protein 3 (Osteogenic);Bone Morphogenetic Protein 3A;BMP-3A;BMP3A;BMP-3
  Molecule Type
Protein coding
  Position On Chromosome
chr4(Start:81030708 - End:81057627)
  Strand
+
  Uniprot Entry
P12645 
  ENSG ID
ENSG00000152785 
    Disease Relevance (Click to Show/Hide)
         2C30: Melanoma of skin Cutaneous Melanoma [Melanoma of skin]
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         8A00: Parkinsonism Parkinson's disease (PD) [Parkinsonism]
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         8A01: Choreiform disorders Huntington's disease (HD) [Choreiform disorders]
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         8A20: Alzheimer disease Alzheimer's disease [Alzheimer disease]
            Detailed Information Disease Link click to show the detail information of this Disease
         CB03: Idiopathic interstitial pneumonitis Idiopathic pulmonary fibrosis (IPF) [Idiopathic interstitial pneumonitis]
            Detailed Information Disease Link click to show the detail information of this Disease
         LD2C: Overgrowth syndromes Sotos syndrome(SS) [Overgrowth syndromes]
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         QA46: Outcome of delivery Fetal intolerance of labor [Outcome of delivery]
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         SE30: Developmental delay disorder CHARGE and Kabuki syndromes [Developmental delay disorder]
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         XH4XG8: Chronic myeloid leukaemia Chronic Phase-Chronic Myeloid Leukemia [Chronic myeloid leukaemia]
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         XH5QN3: Nephroblastoma Wilms tumor [Nephroblastoma]
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         ZERO(Not Found): Glomerular diseases IgA nephropathy [Glomerular diseases]
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Metabolite(s) with this epigenetic modification
  Metabolite Name: Docosahexaenoic acid
     Detailed Information Meta Info click to show the detail information of this Metabolite [1], [2]
     Description
Docosahexaenoic acid could altere the DNA methylation of BMP3 CpG loci.(cg07321467)

References
1 Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597.
2 Arachidonic and oleic acid exert distinct effects on the DNA methylome. Epigenetics. 2016 May 3;11(5):321-34. doi: 10.1080/15592294.2016.1161873. Epub 2016 Apr 18.

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