Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM11897)
  Official Symbol
BCL2L11
  Official Full Name
BCL2 Like 11
  Synonym
BCL2 Like 11;BIM;BOD;BCL2-Like 11 (Apoptosis Facilitator);Bcl-2-Like Protein 11;BimEL;Bcl-2-Related Ovarian Death Agonist;Bcl-2 Interacting Protein Bim
  Molecule Type
Protein coding
  Position On Chromosome
chr2(Start:111119378 - End:111168445)
  Strand
+
  Uniprot Entry
O43521 
  ENSG ID
ENSG00000153094 
    Disease Relevance (Click to Show/Hide)
         2C30: Melanoma of skin Cutaneous Melanoma [Melanoma of skin]
            Detailed Information Disease Link click to show the detail information of this Disease
         8A01: Choreiform disorders Huntington's disease (HD) [Choreiform disorders]
            Detailed Information Disease Link click to show the detail information of this Disease
         8A20: Alzheimer disease Alzheimer's disease [Alzheimer disease]
            Detailed Information Disease Link click to show the detail information of this Disease
         CB03: Idiopathic interstitial pneumonitis Idiopathic pulmonary fibrosis (IPF) [Idiopathic interstitial pneumonitis]
            Detailed Information Disease Link click to show the detail information of this Disease
         QA46: Outcome of delivery Fetal intolerance of labor [Outcome of delivery]
            Detailed Information Disease Link click to show the detail information of this Disease
         XH5QN3: Nephroblastoma Wilms tumor [Nephroblastoma]
            Detailed Information Disease Link click to show the detail information of this Disease
Metabolite(s) with this epigenetic modification
  Metabolite Name: Docosahexaenoic acid
     Detailed Information Meta Info click to show the detail information of this Metabolite [1], [2]
     Description
Docosahexaenoic acid could altere the DNA methylation of BCL2L11 CpG loci.(cg26001287)

References
1 Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597.
2 Arachidonic and oleic acid exert distinct effects on the DNA methylome. Epigenetics. 2016 May 3;11(5):321-34. doi: 10.1080/15592294.2016.1161873. Epub 2016 Apr 18.

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