Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM11849)
  Official Symbol
ABCF1
  Official Full Name
ATP Binding Cassette Subfamily F Member 1
  Synonym
ATP Binding Cassette Subfamily F Member;ABC50;ATP-Binding Cassette;Sub-Family F (GCN20), Member;ATP-Binding Cassette Sub-Family F Member;TNF-Alpha-Stimulated ABC Protein;EST123147;ATP-Binding Cassette 50 (TNF-Alpha Stimulated);TNFalpha-Inducible ATP-Binding Protein;ATP-Binding Cassette 50;EC 3.6.3.17;EC 2.7.7.6;ABC27
  Molecule Type
Protein coding
  Position On Chromosome
chr6(Start:30571393 - End:30597179)
  Strand
+
  Uniprot Entry
Q8NE71 
  ENSG ID
ENSG00000204574 
    Disease Relevance (Click to Show/Hide)
         6B01: Panic disorder Panic Disorder [Panic disorder]
            Detailed Information Disease Link click to show the detail information of this Disease
         8A01: Choreiform disorders Huntington's disease (HD) [Choreiform disorders]
            Detailed Information Disease Link click to show the detail information of this Disease
         8A20: Alzheimer disease Alzheimer's disease [Alzheimer disease]
            Detailed Information Disease Link click to show the detail information of this Disease
         CB03: Idiopathic interstitial pneumonitis Idiopathic pulmonary fibrosis (IPF) [Idiopathic interstitial pneumonitis]
            Detailed Information Disease Link click to show the detail information of this Disease
         LD2C: Overgrowth syndromes Sotos syndrome(SS) [Overgrowth syndromes]
            Detailed Information Disease Link click to show the detail information of this Disease
         SE30: Developmental delay disorder CHARGE and Kabuki syndromes [Developmental delay disorder]
            Detailed Information Disease Link click to show the detail information of this Disease
         XH4XG8: Chronic myeloid leukaemia Chronic Phase-Chronic Myeloid Leukemia [Chronic myeloid leukaemia]
            Detailed Information Disease Link click to show the detail information of this Disease
         XH5QN3: Nephroblastoma Wilms tumor [Nephroblastoma]
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Metabolite(s) with this epigenetic modification
  Metabolite Name: Arachidonic acid
     Detailed Information Meta Info click to show the detail information of this Metabolite [1], [2]
     Description
Arachidonic acid could induce ABCF1 gene hypermethylation in THP-1 cells.

References
1 Dietary metabolites derived from gut microbiota: critical modulators of epigenetic changes in mammals. Nutr Rev. 2017 May 1;75(5):374-389. doi: 10.1093/nutrit/nux001.
2 Dietary proline supplementation alters colonic luminal microbiota and bacterial metabolite composition between days 45 and 70 of pregnancy in Huanjiang mini-pigs J Anim Sci Biotechnol. 2018 Jan 30;9:18. doi: 10.1186/s40104-018-0233-5. eCollection 2018.

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