Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM10474)
  Official Symbol
ERCC2
  Official Full Name
ERCC excision repair 2, TFIIH core complex helicase subunit
  Synonym
EM9;MAG;MGC102762;MGC126218;MGC126219;XPD
  Molecule Type
Protein coding
  Position On Chromosome
chr19(Start:45349837 - End:45370918)
  Strand
-
  Uniprot Entry
P18074 
  ENSG ID
ENSG00000104884 
  Dnmivd Disease
BLCA 
Metabolite(s) with this epigenetic modification
  Metabolite Name: Arachidonic acid
     Detailed Information Meta Info click to show the detail information of this Metabolite [1], [2]
     Description
Arachidonic acid could induce ERCC2 gene hypermethylation in THP-1 cells.

References
1 Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597.
2 Arachidonic and oleic acid exert distinct effects on the DNA methylome. Epigenetics. 2016 May 3;11(5):321-34. doi: 10.1080/15592294.2016.1161873. Epub 2016 Apr 18.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.