Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM10076)
  Official Symbol
EHMT2
  Official Full Name
euchromatic histone lysine methyltransferase 2
  Synonym
G9A;BAT8;GAT8;NG36;KMT1C;C6orf30
  Molecule Type
Protein coding
  Position On Chromosome
chr6(Start:31879759 - End:31897687)
  Strand
-
  Uniprot Entry
A2ABF8 
  ENSG ID
ENSG00000204371 
  Dnmivd Disease
LUSC 
Metabolite(s) with this epigenetic modification
  Metabolite Name: Choline
     Detailed Information Meta Info click to show the detail information of this Metabolite [1], [2]
     Description
Choline deficiencycould hypermethylate the G9a in liver.

References
1 The Virtual Metabolic Human database: integrating human and gut microbiome metabolism with nutrition and disease. Nucleic Acids Res. 2019 Jan 8;47(D1):D614-D624. doi: 10.1093/nar/gky992.
2 Gestational choline supply regulates methylation of histone H3, expression of histone methyltransferases G9a (Kmt1c) and Suv39h1 (Kmt1a), and DNA methylation of their genes in rat fetal liver and brain. J Biol Chem. 2009 Jan 23;284(4):1982-9. doi: 10.1074/jbc.M807651200. Epub 2008 Nov 10.

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