Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM10065)
Official Symbol		ADHFE1
Official Full Name		alcohol dehydrogenase, iron containing, 1
Synonym		ADH8;ADHFe1;FLJ32430;HOT
Molecule Type		Protein coding
Position On Chromosome		chr8(Start:67342420 - End:67383836)
Strand		+
Uniprot Entry		Q8IWW8
Dnmivd Disease		COAD

Metabolite(s) with this epigenetic modification
Metabolite Name: Acetaldehyde
Detailed Information	Meta Info click to show the detail information of this Metabolite	[1], [2]
Description	Acetaldehyde has been shown to promote the hypermethylation of ADHFE1 and methylation-mediated silencing of ADHFE1.

References
1	Relationship between acetaldehyde concentration in mouth air and characteristics of microbiota of tongue dorsum in Japanese healthy adults: a cross-sectional study J Appl Oral Sci. 2019 Jun 13;27:e20180635. doi: 10.1590/1678-7757-2018-0635.
2	Molecular Basis of Alcohol-Related Gastric and Colon Cancer. Int J Mol Sci. 2017 May 24;18(6):1116. doi: 10.3390/ijms18061116.

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