Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM10037)
  Official Symbol
MIR10A
  Official Full Name
microRNA 10a
  Synonym
hsa-mir-10a;MIRN10A
  Molecule Type
miRNA
  Position On Chromosome
chr17(Start:48579838 - End:48579947)
  Strand
-
  ENSG ID
ENSG00000284038 
  Dnmivd Disease
UCEC 
Metabolite(s) with this epigenetic modification
  Metabolite Name: Folate (B9)
     Detailed Information Meta Info click to show the detail information of this Metabolite [1], [2]
     Description
Folate (B9) has been shown to decrease the expression of miR-10a.

Protein(s) with this epigenetic modification
  Protein Name: CagA
     Detailed Information Pro Info click to show the detail information of this protein [3]
     Description
Helicobacter pylori downregulates miR-10a ( 26.70 fold) in a cagA-dependent manner in vitro.

References
1 Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597.
2 Arachidonic and oleic acid exert distinct effects on the DNA methylome. Epigenetics. 2016 May 3;11(5):321-34. doi: 10.1080/15592294.2016.1161873. Epub 2016 Apr 18.
3 Strain-specific suppression of microRNA-320 by carcinogenic Helicobacter pylori promotes expression of the antiapoptotic protein Mcl-1 Am J Physiol Gastrointest Liver Physiol. 2013 Dec;305(11):G786-96. doi: 10.1152/ajpgi.00279.2013. Epub 2013 Oct 17.

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