Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM00487)
  Official Symbol
MIR137HG
  Official Full Name
MIR137 host gene
  Molecule Type
LncRNA
  Position On Chromosome
chr1(Start:97933474 - End:98049863)
  Strand
-
  ENSG ID
ENSG00000225206 
    Disease Relevance (Click to Show/Hide)
         8A40: Multiple sclerosis Multiple sclerosis [Multiple sclerosis]
            Detailed Information Disease Link click to show the detail information of this Disease
         8E49: Postviral fatigue syndrome Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) [Postviral fatigue syndrome]
            Detailed Information Disease Link click to show the detail information of this Disease
         XH3DV3: Adenoma Adenoma [Adenoma]
            Detailed Information Disease Link click to show the detail information of this Disease
         XH8P29: Medulloblastoma Medulloblastoma [Medulloblastoma]
            Detailed Information Disease Link click to show the detail information of this Disease
Metabolite(s) with this epigenetic modification
  Metabolite Name: Docosahexaenoic acid
     Detailed Information Meta Info click to show the detail information of this Metabolite [1], [2]
     Description
Docosahexaenoic acid could altere the DNA methylation of MIR137HG CpG loci.(cg23243552)

Protein(s) with this epigenetic modification
  Protein Name: Rv2966c
     Detailed Information Pro Info click to show the detail information of this protein [3]
     Description
Rv2966c could hypermethylate the non-CpG dinucleotides at the host MIR137HG (geneBody) genetic loci during Mycobacterium tuberculosis H37Rv infection.
  Protein Name: Rv2966c
     Detailed Information Pro Info click to show the detail information of this protein [3]
     Description
Rv2966c could hypermethylate the non-CpG dinucleotides at the host MIR137HG (intergenic) genetic loci during Mycobacterium tuberculosis H37Rv infection.

References
1 Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597.
2 Arachidonic and oleic acid exert distinct effects on the DNA methylome. Epigenetics. 2016 May 3;11(5):321-34. doi: 10.1080/15592294.2016.1161873. Epub 2016 Apr 18.
3 Genome-wide non-CpG methylation of the host genome during M. tuberculosis infection. Sci Rep. 2016 Apr 26;6:25006. doi: 10.1038/srep25006.

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