Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM12407)
Official Symbol		SNORA49
Official Full Name		Small Nucleolar RNA, H/ACA Box 49
Synonym		Small Nucleolar RNA, H/ACA Box 49;ACA49;ACA49 SnoRNA;SNODB1309;SNODB269;RF00562;SNORA49
Molecule Type		RNA Gene
Position On Chromosome		chr12(Start:132031224 - End:132,031,36)
Strand		+
ENSG ID		ENSG00000208892

Metabolite(s) with this epigenetic modification
Metabolite Name: S-Adenosyl Methionine (SAM)
Detailed Information	Meta Info click to show the detail information of this Metabolite	[1], [2]
Description	S-Adenosylmethionine was proved to be decrease SNORA49 methylation in HT-29 cells.(P value = 0.003)

References
1	Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597.
2	Heterochromatinization induced by GAA-repeat hyperexpansion in Friedreich's ataxia can be reduced upon HDAC inhibition by vitamin B3. Hum Mol Genet. 2013 Jul 1;22(13):2662-75. doi: 10.1093/hmg/ddt115. Epub 2013 Mar 7.

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