Details of Epigenetic Molecule(EM)
| General Information of EM (ID: EM11963) | |||||||
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| Official Symbol |
CBFA2T3
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| Official Full Name |
CBFA2/RUNX1 Partner Transcriptional Co-Repressor 3
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| Synonym |
ZMYND4;CBFA2/RUNX1 Partner Transcriptional Co-Repressor 3;MTGR2;MTG16;RUNX1T3;Core-Binding Factor, Runt Domain, Alpha Subunit 2; Translocated To, 3;ETO2;MTG8-Related Gene 2;HMTG16
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| Molecule Type |
Protein coding
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| Position On Chromosome |
chr16(Start:88874858 - End:88977207)
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| Strand |
-
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| Uniprot Entry | |||||||
| ENSG ID | |||||||
| Disease Relevance (Click to Show/Hide) | |||||||
| 2C30: Melanoma of skin | Cutaneous Melanoma [Melanoma of skin] | ||||||
| Detailed Information |
Disease Link
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| 5A02: Thyrotoxicosis | Graves' disease [Thyrotoxicosis] | ||||||
| Detailed Information |
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| 6B01: Panic disorder | Panic Disorder [Panic disorder] | ||||||
| Detailed Information |
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| 8A00: Parkinsonism | Parkinson's disease (PD) [Parkinsonism] | ||||||
| Detailed Information |
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| 8A01: Choreiform disorders | Huntington's disease (HD) [Choreiform disorders] | ||||||
| Detailed Information |
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| 8A20: Alzheimer disease | Alzheimer's disease [Alzheimer disease] | ||||||
| Detailed Information |
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| CB03: Idiopathic interstitial pneumonitis | Idiopathic pulmonary fibrosis (IPF) [Idiopathic interstitial pneumonitis] | ||||||
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| LD2C: Overgrowth syndromes | Sotos syndrome(SS) [Overgrowth syndromes] | ||||||
| Detailed Information |
Disease Link
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| SE30: Developmental delay disorder | CHARGE and Kabuki syndromes [Developmental delay disorder] | ||||||
| Detailed Information |
Disease Link
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| XH4KA9: Burkitt lymphoma | Burkitt Lymphoma [Burkitt lymphoma] | ||||||
| Detailed Information |
Disease Link
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| XH4XG8: Chronic myeloid leukaemia | Chronic Phase-Chronic Myeloid Leukemia [Chronic myeloid leukaemia] | ||||||
| Detailed Information |
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| XH5QN3: Nephroblastoma | Wilms tumor [Nephroblastoma] | ||||||
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| Metabolite(s) with this epigenetic modification | |||||||
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| Metabolite Name: Resveratrol | |||||||
| Detailed Information |
Meta Info
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[1], [2] | |||||
| Description |
Resveratrol could change tumor suppressor gene CBFA2T3 from hypermethylated to hypomethylated status in MDA-MB-231 breast cancer cells treated with resveratrol (100 M) at 48 h.
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