Details of Epigenetic Molecule(EM)
| General Information of EM (ID: EM05040) | |||||||
|---|---|---|---|---|---|---|---|
| Official Symbol |
TAF1L
|
||||||
| Official Full Name |
TATA-box binding protein associated factor 1 like
|
||||||
| Molecule Type |
Protein coding
|
||||||
| Position On Chromosome |
chr9(Start:32629454 - End:32635669)
|
||||||
| Strand |
-
|
||||||
| Uniprot Entry | |||||||
| ENSG ID | |||||||
| Dnmivd Disease | |||||||
| Disease Relevance (Click to Show/Hide) | |||||||
| 2A00: Primary neoplasms of brain | Glioma [Primary neoplasms of brain] | ||||||
| Detailed Information |
Disease Link
 click to show the detail information of this Disease
|
||||||
| 2A90: Mature T-cell lymphoma, specified types, nodal or systemic | Anaplastic large cell lymphoma (ALCL) [Mature T-cell lymphoma, specified types, nodal or systemic] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2B70: Malignant neoplasms of oesophagus | Barrett's esophagus and esophageal adenocarcinoma [Malignant neoplasms of oesophagus] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2B70: Malignant neoplasms of oesophagus | Esophageal adenocarcinoma (EAC) [Malignant neoplasms of oesophagus] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2B80: Malignant neoplasms of small intestine | Small intestinal neuroendocrine tumours (SINETs) [Malignant neoplasms of small intestine] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2B90: Malignant neoplasms of colon | Colon adenocarcinoma [Malignant neoplasms of colon] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2B90: Malignant neoplasms of colon | Colorectal cancer [Malignant neoplasms of colon] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2C25: Malignant neoplasms of bronchus or lung | Lung cancer [Malignant neoplasms of bronchus or lung] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2C30: Melanoma of skin | Cutaneous Melanoma [Melanoma of skin] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2C60: Carcinoma of breast | Breast cancer [Carcinoma of breast] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2D10: Malignant neoplasms of thyroid gland | Thyroid tumors [Malignant neoplasms of thyroid gland] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 4A40: Lupus erythematosus | Systemic lupus erythematosus (SLE) [Lupus erythematosus] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 5B81: Obesity | Obesity [Obesity] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 6A00: Disorders of intellectual development | Intellectual disability and congenital anomalies(ID/CA) [Disorders of intellectual development] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 6A20: Schizophrenia | Schizophrenia [Schizophrenia] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 6E8Z: Mental, behavioural or neurodevelopmental disorders | Psychiatric disorders [Mental, behavioural or neurodevelopmental disorders] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 8A01: Choreiform disorders | Huntington's disease (HD) [Choreiform disorders] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 8A20: Alzheimer disease | Alzheimer's disease [Alzheimer disease] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 8A40: Multiple sclerosis | Multiple sclerosis [Multiple sclerosis] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 9A01: Infectious disorders of eyelid | Human eye and its diseases [Infectious disorders of eyelid] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| BD40: Atherosclerotic chronic arterial occlusive disease | Atherosclerosis [Atherosclerotic chronic arterial occlusive disease] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| CA22: Chronic obstructive pulmonary disease | Chronic obstructive pulmonary disease (COPD) [Chronic obstructive pulmonary disease] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| FA20: Rheumatoid arthritis | Rheumatoid arthritis [Rheumatoid arthritis] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| GA10: Endometriosis | Endometriosis [Endometriosis] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| JA24: Pre-eclampsia | Preeclampsia (PE) [Pre-eclampsia] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| LA02: Spina bifida | Neural tube defects (NTDs) [Spina bifida] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| LD2C: Overgrowth syndromes | Sotos syndrome(SS) [Overgrowth syndromes] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| LD40: Complete trisomies of the autosomes | Down syndrome (DS) [Complete trisomies of the autosomes] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| LD44: Deletions of the autosomes | Deletion or duplication of chromosome 7q11.23 [Deletions of the autosomes] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| MG30: Chronic pain | Fibromyalgia [Chronic pain] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| SD86: Dementia disorder | Dementia [Dementia disorder] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| SE30: Developmental delay disorder | CHARGE and Kabuki syndromes [Developmental delay disorder] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH1E13: Germinoma | Germinoma [Germinoma] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH1XF3: Osteosarcoma | Osteosarcoma [Osteosarcoma] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH3DV3: Adenoma | Adenoma [Adenoma] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH4V32: Ductal carcinoma in situ | Ductal carcinoma in situ (DCIS) [Ductal carcinoma in situ] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH4W48: Hepatocellular carcinoma | Hepatocellular carcinoma (HCC) [Hepatocellular carcinoma] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH68V1: Liver cell adenoma | Hepatocellular adenoma [Liver cell adenoma] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH7F82: Glioblastoma | Glioblastoma [Glioblastoma] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH7PW5: Lymphocytic leukaemia | Pediatric acute lymphoblastic leukemia [Lymphocytic leukaemia] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH7ZQ4: Atypical teratoid/rhabdoid tumour | Atypical teratoid/rhabdoid tumor (ATRT) [Atypical teratoid/rhabdoid tumour] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH85Z0: Neuroblastoma | Neuroblastoma [Neuroblastoma] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH8AA5: Acute myeloid leukaemia | Acute myeloid leukemia (AML) [Acute myeloid leukaemia] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH8P29: Medulloblastoma | Medulloblastoma [Medulloblastoma] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH94U0: Pituitary adenoma | Nonfunctioning pituitary adenomas [Pituitary adenoma] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH9HQ1: Gastrointestinal stromal tumour | Gastrointestinal stromal tumors (GIST) [Gastrointestinal stromal tumour] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| Protein(s) with this epigenetic modification | |||||||
|---|---|---|---|---|---|---|---|
| Protein Name: DNA cytosine methyltransferase | |||||||
| Detailed Information |
Pro Info
click to show the detail information of this protein
|
[1] | |||||
| Description |
DNA cytosine methyltransferase(MTases) could be associated with the decrease GATC-specific methylation in important cancer-specific genes, such as TAF1L.
|
||||||
| Protein Name: Rv2966c | |||||||
| Detailed Information |
Pro Info
click to show the detail information of this protein
|
[2] | |||||
| Description |
Rv2966c could hypermethylate the non-CpG dinucleotides at the host TAF1L (intergenic) genetic loci during Mycobacterium tuberculosis H37Rv infection.
|
||||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.