Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM00045)
  Official Symbol
MIRLET7G
  Official Full Name
microRNA let-7g
  Synonym
LET7G;MIRNLET7G;hsa-let-7g
  Molecule Type
miRNA
  Position On Chromosome
chr3(Start:52302292 - End:52302379)
  Strand
-
  ENSG ID
ENSG00000199150 
  Dnmivd Disease
THCA 
Protein(s) with this epigenetic modification
  Protein Name: CagA
     Detailed Information Pro Info click to show the detail information of this protein [1]
     Description
The cytotoxin-associated gene A (CagA) of Helicobacter pylori enhances EZH2 expression, leading to increased DNA methylation in the let-7 promoter.

References
1 CagA mediates epigenetic regulation to attenuate let-7 expression in Helicobacter pylori-related carcinogenesis Gut. 2013 Nov;62(11):1536-46. doi: 10.1136/gutjnl-2011-301625. Epub 2012 Aug 30.

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