Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM00011)
  Official Symbol
TP53
  Official Full Name
tumor protein p53
  Synonym
LFS1;p53
  Molecule Type
Protein coding
  Position On Chromosome
chr17(Start:7661779 - End:7687538)
  Strand
-
  Uniprot Entry
P04637 
  ENSG ID
ENSG00000141510 
  Dnmivd Disease
PRAD 
Protein(s) with this epigenetic modification
  Protein Name: HP0175
     Detailed Information Pro Info click to show the detail information of this protein [1], [2]
     Description
HP0175 responsible for IL-6 expression could be support the maintenance of p53 tumor suppressor gene promoter methylation.

References
1 Histone modifications and chromatin remodeling during bacterial infections. Cell Host Microbe. 2008 Aug 14;4(2):100-9. doi: 10.1016/j.chom.2008.07.009.
2 Interleukin 6 supports the maintenance of p53 tumor suppressor gene promoter methylation Cancer Res. 2005 Jun 1;65(11):4673-82. doi: 10.1158/0008-5472.CAN-04-3589.

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