Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM00007)
  Official Symbol
BIRC5
  Official Full Name
baculoviral IAP repeat containing 5
  Synonym
API4;EPR-1;survivin
  Molecule Type
Protein coding
  Position On Chromosome
chr17(Start:78214186 - End:78225636)
  Strand
+
  Uniprot Entry
A0A0B4J1S3 
  ENSG ID
ENSG00000089685 
  Dnmivd Disease
LUSC 
Protein(s) with this epigenetic modification
  Protein Name: HP0175
     Detailed Information Pro Info click to show the detail information of this protein [1], [2]
     Description
HP0175 responsible for IL-6 expression could be increase the Survivin gene promoter methylation.

References
1 Histone modifications and chromatin remodeling during bacterial infections. Cell Host Microbe. 2008 Aug 14;4(2):100-9. doi: 10.1016/j.chom.2008.07.009.
2 Interleukin-6 contributes to growth in cholangiocarcinoma cells by aberrant promoter methylation and gene expression Cancer Res. 2006 Nov 1;66(21):10517-24. doi: 10.1158/0008-5472.CAN-06-2130.

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