Target General Information
Target ID	T50066
Target Name	Chloride channel protein 2
Synonyms	ClC-2; ClC-2 Cl- channel; ClC-2 chloride channel; CLCN2
Target Type	Successful
Gene Name	CLCN2
Biochemical Class	Chloride channel
UniProt ID	CLCN2_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Alopecia
Example drug	RK-023			Phase 2	[548944], [1572592]
Tissue	Skin from scalp
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.01 Z-score: -0.06 P-value: 8.78E-02
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Disease	Irritable bowel syndrome
Tissue	Rectal colon tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.35 Z-score: -0.62 P-value: 9.63E-03
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref
Ref 548944	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800030641)
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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