Target General Information
Target ID	T48873
Target Name	Synaptic vesicle amine transporter
Synonyms	Monoamine transporter; Solute carrier family 18 member 2; VAT; VMAT; Vesicular Monoamine Transporter ; Vesicular amine transporter; SLC18A2
Target Type	Successful
Gene Name	SLC18A2
Biochemical Class	Major facilitator superfamily
UniProt ID	VMAT2_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Alzheimer's disease
Example drug	AV 133			Phase 3	[548627], [1572592]
Tissue	Entorhinal cortex
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.04 Z-score: -0.11 P-value: 2.69E-02
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Reference
Ref 548627	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027191)
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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