Target General Information
Target ID	T26368
Target Name	GABA(A) receptor alpha-5
Synonyms	GABA-A alpha-5; GABAA alpha 5; GABRA5
Target Type	Clinical Trial
Gene Name	GABRA5
Biochemical Class	Ligand-gated ion channel
UniProt ID	GBRA5_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Alzheimer's disease
Example drug	RG-1662			Phase 2	[525248], [1572592]
Tissue	Entorhinal cortex
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.68 Z-score: -0.61 P-value: 3.15E-09
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 525248	ClinicalTrials.gov (NCT02484703) A Study of RG1662 in Down Syndrome Among Children 6 to 11 Years of Age.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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