Drug Information

Drug General Information
Drug ID
D0D3BO
Former ID
DIB006311
Drug Name
SOLPECAINOL HYDROCHLORIDE
Synonyms
EGYT-2936; Solpecainol hydrochloride < Rec INNM >; Rac-threo-2-(1-Methyl-2-phenoxyethylamino)-1-phenyl-1,3-propanediol hydrochloride; Rac-[1R*,2S*(S*)]-2-[(1-Methyl-2-phenoxyethyl)amino]-1-phenyl-1,3-propanediol hydrochloride
Drug Type
Small molecular drug
Indication Cardiac arrhythmias [ICD9: 427; ICD10:I47-I49] Discontinued in Phase 2 [545414]
Formula
C18H24ClNO3
Canonical SMILES
CC(COC1=CC=CC=C1)NC(CO)C(C2=CC=CC=C2)O.Cl
InChI
1S/C18H23NO3.ClH/c1-14(13-22-16-10-6-3-7-11-16)19-17(12-20)18(21)15-8-4-2-5-9-15;/h2-11,14,17-21H,12-13H2,1H3;1H/t14-,17-,18+;/m0./s1
InChIKey
ZERZMJPMHWGYET-QSCFYETBSA-N
PubChem Compound ID
6918180
PubChem Substance ID
12014577, 43529570, 50475025, 114787559, 227461554
Target and Pathway
Target(s) Sodium channel Target Info Modulator [550841], [551871]
KEGG Pathway Dopaminergic synapse
Reactome Interaction between L1 and Ankyrins
References
Ref 545414Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003158)
Ref 550841US patent application no. 2002,0102,217, Diagnostic,therapeutic agents.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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