Drug Information

Drug General Information
Drug ID
D0H8PX
Former ID
DIB015411
Drug Name
MORAb-066
Synonyms
Anti-tissue factor monoclonal antibody (pancreatic tumor), Morphotek
Drug Type
Antibody
Indication Pancreatic cancer [ICD9: 140-199, 140-229, 157, 210-229; ICD10:C25] Phase 1 [524176]
Company
Eisai
Target and Pathway
Target(s) Tissue factor Target Info [551163]
KEGG Pathway Complement and coagulation cascades
NetPath Pathway IL4 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
TWEAK Signaling Pathway
PANTHER Pathway Angiogenesis
Blood coagulation
PathWhiz Pathway Coagulation
Reactome Extrinsic Pathway of Fibrin Clot Formation
WikiPathways Complement and Coagulation Cascades
Formation of Fibrin Clot (Clotting Cascade)
References
Ref 524176ClinicalTrials.gov (NCT01761240) Dose Escalation Study MORAb-066 Targeting TF-expressing Malignancies Including Breast, Pancreatic, Colorectal, NSCLC. U.S. National Institutes of Health.
Ref 551163Clinical pipeline report, company report or official report of Morphotek.

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