Drug Information

Drug General Information
Drug ID
D01BZR
Former ID
DIB008161
Drug Name
IC-041
Synonyms
Small molecule PDE 1 inhibitors (cognitive disorder), Intra-Cellular Therapies; PDE 1B inhibitor (small molecule therapeutic, cognitive disorder), Intra-Cellular
Indication Cognitive disorders [ICD9: 290-294, 294.0, 780.09, 780.9, 780.93; ICD10:F01-F07, F04, F05, R41.3] Investigative [543401]
Company
Intra-Cellular Therapies Inc
Target and Pathway
Target(s) Phosphodiesterase (PDE) 1B Target Info Inhibitor [543401]
KEGG Pathway Purine metabolism
Calcium signaling pathway
Morphine addiction
Reactome cGMP effects
G alpha (s) signalling events
WikiPathways G Protein Signaling Pathways
DAG and IP3 signaling
Opioid Signalling
References
Ref 543401(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1295).
Ref 543401(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1295).

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