Drug Information

Drug General Information
Drug ID
D0U3YW
Former ID
DIB014352
Drug Name
ADC-9971
Synonyms
ADS-9971; CRTh2 antagonist (oral, COPD/allergic asthma/allergic rhinitis), Argenta Discovery; Prostaglandin D2 receptor antagonist (oral, allergic asthma/allergic rhinitis/COPD), Argenta Discovery
Indication Allergic rhinitis [ICD9: 472.0, 477, 995.3; ICD10:J00, J30, J31.0, T78.4] Investigative [543776]
Company
Argenta Discovery Ltd
Target and Pathway
Target(s) Putative G-protein coupled receptor 44 Target Info Antagonist [543776]
Reactome Prostanoid ligand receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 543776(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 339).
Ref 543776(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 339).

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