TTD | Drug: D03VWB

Drug General Information
Drug ID	D03VWB
Former ID	DIB005133
Drug Name	MP-157
Indication	Hypertension [ICD9: 401; ICD10:I10-I16]		Phase 1	[549248]
Company	Mitsubishi Tanabe Pharma Corp
Target and Pathway
Target(s)	Type-2 angiotensin II receptor	Target Info	Agonist	[549742]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Adrenergic signaling in cardiomyocytes
	Renin-angiotensin system
Reactome	Peptide ligand-binding receptors
Reactome	G alpha (i) signalling events
WikiPathways	ACE Inhibitor Pathway
	GPCRs, Class A Rhodopsin-like
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 549248	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034178)
Ref 549742	As drug target reemerges, the question is to block or stimulate it. Nature Medicine. Spoonful of Medicine. 05 Feb 2014. Cassandra Willyard

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Drug Information