Drug Information

Drug General Information
Drug ID
D0A6YN
Former ID
DIB016242
Drug Name
SUN-C5174
Synonyms
5-[3-[4-(4-Fluorophenyl)piperazin-1-yl]propyl]-8(S)-hydroxy-1-methyl-1,4,5,6,7,8-hexahydropyrrolo[3,2-c]azepin-4-one
Indication Peripheral vascular disease [ICD9: 443.9; ICD10:I73.9] Discontinued in Phase 2 [547072]
CAS Number
CAS 191592-36-6
Target and Pathway
Target(s) 5-HT 2 receptor Target Info Antagonist [525776]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Serotonergic synapse
Inflammatory mediator regulation of TRP channels
References
Ref 547072Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800012828)
Ref 525776Synthesis and serotonin 2 (5-HT2) receptor antagonist activity of 5-aminoalkyl-substituted pyrrolo[3,2-c]azepines and related compounds. Chem Pharm Bull (Tokyo). 2000 May;48(5):623-35.

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