Drug Information

Drug General Information
Drug ID
D0X1ZV
Former ID
DNC001471
Drug Name
Trimidox
Drug Type
Small molecular drug
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Preclinical [545781]
Formula
C7H8N2O4
Canonical SMILES
C1=C(C(=O)C(=CC1=C(N)NO)O)O
InChI
1S/C7H8N2O4/c8-7(9-13)3-1-4(10)6(12)5(11)2-3/h1-2,9-11,13H,8H2
InChIKey
XNZIUZXTCXGBPF-UHFFFAOYSA-N
CAS Number
CAS 95933-74-7
PubChem Compound ID
5464467
PubChem Substance ID
634610, 14772793, 15243733, 39460737, 46204509, 49879406, 50396463, 53787522, 57363650, 104240736, 114007759, 125717229, 127315491, 127315492, 127315493, 128641228, 132560655, 134340585, 134340650, 135030432, 137106448, 137385079, 163211993, 177749061, 227839302, 230121922, 252469565
Target and Pathway
Target(s) Ribonucleoside-diphosphate reductase Target Info Inhibitor [535574]
References
Ref 545781Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004681)
Ref 535574Suppression of retrovirus-induced immunodeficiency disease (murine AIDS) by trimidox and didox: novel ribonucleotide reductase inhibitors with less bone marrow toxicity than hydroxyurea. Antiviral Res. 2002 Nov;56(2):167-81.

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