Drug Information

Drug General Information
Drug ID
D07LWT
Former ID
DIB011807
Drug Name
FE-202767
Synonyms
Oxytocin agonists (erectile dysfunction), Ferring
Indication Erectile dysfunction [ICD9: 302.72, 607.84; ICD10:F52.2, N48.4] Phase 2 [525314]
Company
Ferring Pharmaceuticals Inc
Canonical SMILES
c1cccc2c1Nc1c(CN2C(=O)c2ccc(c(c2)C)CNC(=O)N2[C@@H](CCC2<br />)C(=S)N2CCN(CCC2)C)cnn1C
Target and Pathway
Target(s) Oxytocin receptor Target Info Agonist [543799]
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Oxytocin signaling pathway
NetPath Pathway TGF_beta_Receptor Signaling Pathway
PANTHER Pathway Oxytocin receptor mediated signaling pathway
Reactome Vasopressin-like receptors
G alpha (q) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Myometrial Relaxation and Contraction Pathways
Oxytocin signaling
Gastrin-CREB signalling pathway via PKC and MAPK
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 525314ClinicalTrials.gov (NCT02545127) Trial Exploring the Efficacy and Safety of FE 202767.
Ref 543799(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 369).

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