Drug Information

Drug General Information
Drug ID
D08EES
Former ID
DIB006142
Drug Name
XR-5000
Synonyms
DACA; SN-22995
Indication Colorectal cancer [ICD9: 153, 154; ICD10:C18-C21] Phase 2 [526364]
Company
Xenova
Canonical SMILES
n1c2c(C(=O)NCCN(C)C)cccc2cc2c1cccc2.Cl.Cl
Target and Pathway
Target(s) Toposisomerase-1 Target Info Modulator [526364]
DNA topoisomerase II Target Info Modulator [526364]
NetPath Pathway IL2 Signaling Pathway
PANTHER Pathway DNA replication
Pathway Interaction Database Caspase Cascade in Apoptosis
WikiPathways Integrated Pancreatic Cancer Pathway
References
Ref 526364Phase II study of XR5000 (DACA) administered as a 120-h infusion in patients with recurrent glioblastoma multiforme. Ann Oncol. 2002 May;13(5):777-80.
Ref 526364Phase II study of XR5000 (DACA) administered as a 120-h infusion in patients with recurrent glioblastoma multiforme. Ann Oncol. 2002 May;13(5):777-80.

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