TTD | Drug: D0P6YO

Drug General Information
Drug ID	D0P6YO
Former ID	DIB009953
Drug Name	NSD-721
Synonyms	NS-11394; NS-2552; NS-2664; GABA-A receptor modulators, NeuroSearch; GABA-A receptor modulators, NeuroSearch/Meiji Seika
Indication	Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42]		Terminated	[546776]
Company	NeuroSearch A/S
Canonical SMILES	CC(C)(c1cc2ncn(c3cc(ccc3)c3c(cccc3)C#N)c2cc1)O
CAS Number	CAS 468060-99-3
Target and Pathway
Target(s)	GABA A receptor	Target Info	Modulator	[543814]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Retrograde endocannabinoid signaling
	GABAergic synapse
	Morphine addiction
	Nicotine addiction
Reactome	Ligand-gated ion channel transport
Reactome	GABA A receptor activation
WikiPathways	SIDS Susceptibility Pathways
	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
	Iron uptake and transport
References
Ref 546776	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010233)
Ref 543814	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 415).

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Drug Information