Drug Information

Drug General Information
Drug ID
D0Z2MB
Former ID
DCL000087
Drug Name
Cilansetron
Synonyms
Calmactin; DU-123265; KC-9946; Cilansetron (USAN/INN)
Drug Type
Small molecular drug
Indication Irritable bowel syndrome [ICD9: 564.1, 787.91; ICD10:A09, K58, K59.1] Phase 3 [536224], [539448]
Company
Solvay Pharma
Formula
C20H21N3O
InChI
InChI=1S/C20H21N3O/c1-13-21-9-11-22(13)12-15-7-8-17-18(20(15)24)16-6-2-4-14-5-3-10-23(17)19(14)16/h2,4,6,9,11,15H,3,5,7-8,10,12H2,1H3/t15-/m1/s1
InChIKey
NCNFDKWULDWJDS-OAHLLOKOSA-N
CAS Number
CAS 120635-74-7
PubChem Compound ID
6918107
PubChem Substance ID
12014360, 14752623, 14899250, 17194680, 17397631, 43529502, 50165531, 57371801, 134338784, 135025200, 135650097, 136036427, 137249400, 139842564, 141065188, 160687005, 175426888, 179149696, 198944242, 226406197
SuperDrug ATC ID
A03AE03
Target and Pathway
Target(s) 5-hydroxytryptamine receptor 3A Target Info Modulator
KEGG Pathway Serotonergic synapse
NetPath Pathway IL2 Signaling Pathway
PANTHER Pathway 5HT3 type receptor mediated signaling pathway
Reactome Ligand-gated ion channel transport
WikiPathways SIDS Susceptibility Pathways
Iron uptake and transport
References
Ref 536224Emerging drugs for irritable bowel syndrome. Expert Opin Emerg Drugs. 2006 May;11(2):293-313.
Ref 539448(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2297).

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.