Drug Information

Drug General Information
Drug ID
D09CFM
Former ID
DIB007197
Drug Name
DANOFLOXACIN
Synonyms
BAN; CP-76136; Danofloxacin < Rec INN; CP-76136-27 (mesylate); 1-Cyclopropyl-6-fluoro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Drug Type
Small molecular drug
Indication Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10:A00-B99] Discontinued in Phase 2 [526405]
Formula
C19H20FN3O3
Canonical SMILES
CN1C[C@@H]2C[C@H]1CN2c3cc4N(C=C(C(=O)O)C(=O)c4cc3F)C5CC<br />5
InChI
1S/C19H20FN3O3/c1-21-7-12-4-11(21)8-22(12)17-6-16-13(5-15(17)20)18(24)14(19(25)26)9-23(16)10-2-3-10/h5-6,9-12H,2-4,7-8H2,1H3,(H,25,26)/t11-,12-/m0/s1
InChIKey
QMLVECGLEOSESV-RYUDHWBXSA-N
CAS Number
CAS 112398-08-0
PubChem Compound ID
71335
Target and Pathway
Target(s) Bacterial DNA gyrase Target Info Modulator
References
Ref 526405Pharmacokinetic and pharmacodynamic profiles of danofloxacin administered by two dosing regimens in calves infected with Mannheimia (Pasteurella) haemolytica. Antimicrob Agents Chemother. 2002 Sep;46(9):3013-9.

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