Drug Information

Drug General Information
Drug ID
D00RJB
Former ID
DIB014546
Drug Name
Rilopirox
Synonyms
Riloprox; Hoe-351
Drug Type
Small molecular drug
Indication Fungal infections [ICD9: 110-118; ICD10:B35-B49] Phase 2 [546060]
Company
Hoechst AG
Formula
C19H16ClNO4
Canonical SMILES
n1(c(cc(cc1=O)C)COc1ccc(Oc2ccc(Cl)cc2)cc1)O
CAS Number
CAS 104153-37-9
PubChem Compound ID
71778
Target and Pathway
Target(s) Arachidonate 5-lipoxygenase Target Info Inhibitor [529413]
BioCyc Pathway Aspirin-triggered lipoxin biosynthesis
Resolvin D biosynthesis
Leukotriene biosynthesis
Lipoxin biosynthesis
Aspirin triggered resolvin D biosynthesis
Aspirin triggered resolvin E biosynthesis
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
Serotonergic synapse
Ovarian steroidogenesis
Toxoplasmosis
NetPath Pathway IL4 Signaling Pathway
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Vitamin D Receptor Pathway
Arachidonic acid metabolism
Eicosanoid Synthesis
Selenium Micronutrient Network
References
Ref 546060Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006112)
Ref 529413Therapy of seborrheic eczema with an antifungal agent with an antiphlogistic effect. Mycoses. 1991;34 Suppl 1:91-3.

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